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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '219f63fb10eacae841ae767d928dac9b60b7dd874f5c46d0d3283af2522cd8b7' 
  AND token = '4qMPbWN22JbXE4HFkFTU39unf+n+fD0vP6yAm8GSjCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}