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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53eec5e5b6527d46dec1167d68e1e0fc1e1c9e096ceeb0ce9218b9e0ba2c2fbf' 
  AND token = 'nRY7X+2gOQOsPrlj+ti+rMRAxuIDZBNy403R2pRmZDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}