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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee9c6516b04c74778a08b60f7e43b0ecc3adcecfa5027f34a3fa4e7b3f7e0b4b' 
  AND token = 'sFr7JcjmVzQIEznjINwWtDkJRrSiwzE0Gs5u3AJo998=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}