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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50eb0161b2db341d3e91fcca993a2d8450a3c0bf3e6d9afa101466c3165ee3cb' 
  AND token = 'Zl5xFAQCNqCMt7GAeCuZYTjKeSeWcdu/R6mcqSf820Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}