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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9325b053a4d4be5e1efd0b63e91b1ad7e1889b286add6d8c2b2b53255c0bdeb' 
  AND token = 'QskR9akxAKIam52I5vSSDacnEHpDQUFF+xd2l50Az78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}