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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5a138f32c856ba3b696621e3c0181d54932f69d726553b4ff61f863d99d6f3d' 
  AND token = '+ASc91wNBCxfa+sB4LNQ++nxQG3du6FS6rv4kAIswk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}