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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59d1cb0318b50d9e51d1d8f3841a8da0dc353c1a844034529f2bbee25df70991' 
  AND token = '0adqFqZb95fp7BKgUQjscBOg1pNc9jAuVk8kiyz0jGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}