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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5583943f277e6b1a4eae2f5b7f18c729c43eee66d14204934d3979395635adf1' 
  AND token = 'Q0cObdVKCaDzSo16oOhEw2K18GpGrRP/+eEsswS9PYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}