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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e9b9885d84ca1cf5dc742d4e0b69332205de470f1d404915cb3c1bb72eaba2a' 
  AND token = 'hhLEip3hx/G9/lLjHRQpMq1a3+ICcXA1GiYEhbMTssc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}