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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2df5d3fcd3a3a3376bfae1480587cba347d1e3e8f0233f447f47793258e07949' 
  AND token = 'DTJ8JLMORSqcVoP5wXC4aN8k1OB3YOxCRSr7f05/Jlg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}