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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab8b18441c1e5b31938d53d7160048dea8ca438eac93eb71d5c7600079a36a11' 
  AND token = 'wOfTy0DKSZIcXfBEAlcW6l4k4Z2BYGwNdzVsYjQyChg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}