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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39a28cb67bd3ac505e1b2fdf249321dac0b67bdad54d75193d437e8ade970584' 
  AND token = 'RYkuaHA5tKI0XkFGAePyA0v3Fu0xCqjCHOZ6E//s5vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}