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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b9b388e81a61812271a4515fdbf71c6f7cbbe4e6ac73fc4782ce41ab3139849' 
  AND token = 'hY4zRVhphwYtV+XytnfR+tbxtDeCs6gKWUW95p0edIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}