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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a8cf4de0b1252579539c443a8cb243d37056071517a7412a7995dd648274828' 
  AND token = 'jW5/mX+qIpA468FXCvuqZo10HdXqcOqiqfoSxjU+3ok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}