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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ee113b46a59ebfbcdfaf77bed0cdca6a009ce857bf12d0033b1639abc72d2d7' 
  AND token = 'pmtw1/qj7mg5wSmLYg9lK6u2i3tjZOA1YCSUfWuOoxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}