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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01105f2c6ede4c5f0cc82a32b36401babd385917af9bf6c87d3d32f9a7e1fbe4' 
  AND token = 'lmgCVNJoxuUDbLGsBDXmajanaYtpm0PXshYtmOaP28I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}