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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab002b46b51bb11d883dbf1c227f21439db0c0be7cecea3d8f514c11d8340809' 
  AND token = 'ojVhiTghE2F2vSi+I35/Cmn3cffE/IMLG8diY1a9bjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}