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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38a200dcab6ae206e1ebc062f46b07543e4d9d7b47536e00b7ed69676901f8b8' 
  AND token = 'c2IMUZ+NMQ2mP4NWRKMl6Q3OIlJv96wUdrwndydnI7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}