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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adf1ad2fbc1a721f8b6cb32ebc58802ece592a9784080b3c1db3eec4f6547b6b' 
  AND token = 'z4TbR4UxkjCpJ9XOoWs6UFaSLJQsw1DWfycbCczfBcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}