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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67e8e2c992b328e49fa0b38c306bac872a4539d7d82f5b5c8938ac3a4921d32d' 
  AND token = '8ASAFAxPD6xDySCuUMzwwZKbLT3Wy6xeqxR6oZbw3OY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}