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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7c50cd1ad8cd5c5d68a02f4d58bba42b1775842c79dd5edb7e53e5a3d1b5d4d' 
  AND token = '2IJ69wT0Giz8Jmmh+JM39tAo+eOsYekhQPgIcJYK0UQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}