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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7f7e3e09a216a9b3f7f2ba7ad443e38e1d87d8d4c22f4a118da17772585f47e' 
  AND token = 'QCCxwom2h/UnX8erA4+wtlV5kV2xmIaerbCN04kIM2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}