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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ce44739fa4c619ea3ed9a181c043bd3e1b0a4746496c6bc37411f80c45ba39e' 
  AND token = 'zZleCSLuXjOvXp5VDkcctk3LX5Vj5VQ61G9rkOz2YCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}