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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a545988c1296519c7f21be37d2a889944a2522d7029155b378c99dca8d925f4' 
  AND token = 'gJbe4uQcQXCkiMmBkJEmCWtdVz3YFGR4vW3ndLEyjAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}