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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11dd9104da27c45c0de6c733ac488bea7e61dff1aa51ab3f3f591cf8f97fb9c7' 
  AND token = '4+MwO4DlKnB18ndfG0RDv5jZQ8kMXaew3okhbzoT0CA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}