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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce3bfd281588f6203b64d28a55d67df02a0754da7559e2b5a2067691a4098ce2' 
  AND token = 'P+LFT6I86/EQhsiEwieHnvBMa7RtOwhvrQ43OhSWiU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}