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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf59047ca8baa808cfa5c8cc9032e36fd61c8891cd34ceefe623fa298fedbbb1' 
  AND token = 'tOAjiSl3FClSi/6nUO8IShusgW0rZXNHf/bVFpp8zWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}