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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0465c6013d74672ac66dfc06fbd3b8e7d18a33561337e3d01f8ff65b76e0f489' 
  AND token = 'HDhGeTfe/k3Ug/SMUj0exmtnAyLMXuX8h2y/tKETBV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}