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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22556a9e772d3a7869a5865c5b7acd206f0bbb90c449b84eead076b15f231fae' 
  AND token = 'iCC0eb3cp/M3HnL5RVgyqjRsht2gS5D6wRPNi0mnqCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}