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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1b363c7d1344e8c21e72ef777331c3ff060286da92aa47699ad400218fe0c8c' 
  AND token = 'CJxofM01E5bposS9Zx8Yv99Ul9SFpGItLm5CyIWAzXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}