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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd409e59d08aa961db7f54a9e5a9327e186860d249d17ca3c0aeb1b0a9229b4a5' 
  AND token = '16Igu33vq6R/eTWhUavCYWylIDig+pU2FWFEqyTESA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}