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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6226d759016c3af25af79432e10025cf8365ddcace6c60c0bfa157dc5601ae34' 
  AND token = 'OMf0Uo3o8VC2oCy3qfznj9bPACVrCRbguwgKBAiyF6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}