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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67e51cba18581332ddffc8319ce564f7903f1bafb9d74486cdf15a95b90defb0' 
  AND token = '+FhZ0vt+LMA4+XLG1Y5A9dyCfgExeZ/Rjws8Uep0J9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}