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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07ce8457b875cc50d341183b83b346e0da5aad5635d60b47d31f99e68f075b1a' 
  AND token = '1/LwSPuJQB/RI+bvrG7XjpHtTtnfH1fD4bUptEGKxZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}