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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e311893395a25d0e3d7054b38280b924c5b147e6f2bb7402abe9ffa6529a27a5' 
  AND token = 'sQjDREvWfBasdMA0JDL+thTFFkW0sBmPxPDRp9Eu/QQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}