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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21f5064f3666cd52a3bc524f7e81419d351b51d7644455922ac51974b5f3c624' 
  AND token = 'ffk4SerXptRPzeIuH2961QE3lJ9Af2ko129LlQiTwfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}