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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c5f1a756f95cfa2d5414977f2d13392c764ca462b95f301910c9dd91b04dcbb' 
  AND token = 'Ma9dlAFmYqdMcZMsU5tBmxSi8DkQJZYo/JVitce9nw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}