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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '492a6b73b51a781a31e683970bae4044fb88eede8e62f808c2676198cfefff36' 
  AND token = 'KQQ1ZGBujB4ORO0C4EElHkmsmUdaW/V8Z1y+2MeIpYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}