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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cac88e24d9e4ffecb8c7406959e3e6596e20a7abbb4fac812142c06852529bd' 
  AND token = 'fIfSy1xjZ6MAJ5pOxya52uCRb6g8/tCpn+iCPSANkMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}