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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42c51664a935cbf739aba3d34f5697d4ec72ce535575b427c0de307d8727e810' 
  AND token = 'vJZhPaENJFrNrsQqmEyewFQ/+uePB8TXrf4wO0QtD0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}