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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6108fd5c4fd7e1ec0d78e1ccc719067e4559b67c4d840295bce81be6dff88e2' 
  AND token = 'GU9+fR5uLhzsSfrNn+JeaX8b6rLJYLi4ZzlhrV9su14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}