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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6d9104b20ac19535cbd6f41d7b1a465312086eff2da8b49615c8dd21394279c' 
  AND token = 'RSl1JuD/rQAgZkndVkAXuRf1MTLA2ycJG6nHGG+on4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}