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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '527a44cd6e1c7c7dc701b56293717b612ac14000233db03e6803d15de6d41ef3' 
  AND token = 'oGsXiz5+19psLc+uF3l9utW0rW6gfZAEslROqJ8xUXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}