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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e8963e32769ab7c1900e011af9231990e54e652ca27bb44a22f9067f1b52e56' 
  AND token = 'Qf8FD60KLJuZSC1lWBO7nx6X2LYPOSPGeucPWXw53Ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}