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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53b93c225b55cdf033aa0b3da006d8f86958ab33bb20d62172c3d024d9a263f6' 
  AND token = 'xImAa9iQM+IZ6tS9yTsgD3vTjMYLTFMONXrzczlh+E0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}