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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6271985efc83c579c99ce6489c40135bd08bb0cfd67f16fb8624a9abca3890f2' 
  AND token = 'Juoh64vm93CqZfHXmDArm7IftssTWrg7yBFhfxo/dC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}