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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a915d73be6150c41595a91a1d89c8620834b86b11f16749837e779eaa279e520' 
  AND token = '2VluaV1aTUkPg7g5kaf1FOJh4Qwt4zSV1sQ2Mf9IDug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}