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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4b5e3d931030c890e70605c1833f7366492ad32a2aa945c4bb38e3609e9385c' 
  AND token = 'cl7UD428W1rIynUSjP4HwoMy+IeSv2XZx/0s9yUTiSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}