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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81b683794ee5dca5c17c3c4aad0cacc7b2bbb8aba5183030d112dc00635e00e6' 
  AND token = 'n4uLoDsMKm1T3VNT4asguY7V3Vxrk5r9N2AEioMWW2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}