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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cab37159e69bd97cec810c33d992ab40ba5a491341cc7f527e0e902540b4554' 
  AND token = 'qB0JVX1rVPoJyTUPcyAJOxxYxkUabE4l1+z8GAXebrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}